The Best Nootropics For Memory Enhancement

Nick J-Pepe

03/21/2020

If you're looking for the best nootropics for memory enhancement, you have come to the right place. Many people take nootropics to boost their memory, and there is no dearth of choices in the market.

However, some memory nootropics have been specifically designed for improving the manner in which the brain makes new memories as well as recall the old memories.

​In this article, you will come to know about the best nootropics available in the market for enhancing your memory as well as some nootropic stacks that can help you get better results.

As far as memory improvement is concerned, there are several cognitive factors that you need to understand before you begin this journey.

Top 5 Best Selling Nootropic Supplements Reviewed

1) Doctor's Best Natural Brain Enhancers

Doctor's Best Natural Brain Enhancers, Non-GMO, Vegan, Gluten Free, 60 Veggie Caps

Product Overview

  • Science-based nutrition;
  • Nootropics supplements promote memory and attention;
  • Vegan;
  • Non-GMO and gluten-free.

What Is Doctor's Best Natural Brain Enhancers PS & GPC

GPC (GlyceroPhosphoCholine) and PS (PhosphatidylSerine) have several proven benefits to various cognitive functions. These phospholipid nutrients work very well together, due to their different mechanisms of action.

 GPC can be found in its highest concentrations inside the cells, while PS helps to build the cell membranes that supply the brain with electricity and vital energy. The benefits of GPC and PS have been evidenced in multiple random, double-blind trials. These nutrients are proven to be effective in humans of all ages.

The Advantages of Doctor's Best Natural Brain Enhancers

  • Improve various cognitive functions such as attention, memory and learning ability;
  • Helps the brain to cope with stress;
  • Enable growth factor action for the renewal of the brain circuits.

How to Use This Product

Take 2 capsules daily between meals, not later than 4 pm. Intakes up to 6 capsules per day may be beneficial.

2) Jarrow Formulas Neuro Optimizer

Jarrow Formulas Neuro Optimizer, Supports Brain Health and Function*, 120 Capsules

Product Overview

  • Nootropic supplements support brain health and function;
  • Dietary supplement;
  • Gluten free.

What Is Jarrow Formulas Neuro Optimizer

Jarrow Formulas Neuro Optimizer is pure food for the brain, thanks to its unique combination of nutrients that accelerate brain metabolism and offer effective antioxidant protection in a safe and natural way. 

Citicoline (CDP-Choline) promotes the synthesis of phosphatidylcholine, one of the main compounds in the gray matter of our brains. Citicoline acts as a catalyst in the synthesis of acetylcholine, being, therefore, a brain metabolism promoter and an effective phospholipid generator.

PS (Phosphatidylserine) helps to promote neural communication while being also very effective in improving the brain's response to stress. The antioxidant substances are actively fighting oxidative processes in the brain, therefore protecting the neurons against oxidation. 

Acetyl-L-Carnitine and L-Glutamine are also regulators of energy utilization.  Taurine is important in intracellular osmoregulation, which means it helps to maintain the healthy concentrations of ions inside the cells.  

How to Use This Product

Take 4 capsules per day with juice or water between meals.

3) Now Foods Brain Elevate

NOW Supplements, Brain Elevate, Featuring Ginkgo Biloba, RoseOx and Phosphatidyl Serine, 120 Veg Capsules

Product Overview

  • Cognitive health;
  • With memorzine Huperzine A, Alpha-GPC & Phosphatidylserine;
  • Supports memory, learning, and alertness;
  • Dietary supplement;
  • Vegetarian/vegan;
  • GMP quality assured.

What Is Now Foods Brain Elevate

Foods Brain Elevate is a supplement from the nootropics category that promotes mental alertness and learning, thanks to its ability to stimulate the production and the activity of Acetylcholine (ACh).

ACh is one of the most important neurotransmitters, with a major role in regulating cognitive and neural function. ACh production tends to decrease as we age. 

The Alpha-GPC combination in Brain Elevate as the ability to boost Acetylcholine production with Memorzine Huperzine A, thus maintaining ACh levels in the brain.

​This supplement also includes Phosphatidylserine, a compound that plays an important role in supporting the health of membranes and the efficiency of nerve cell signaling.

How to Use This Product

As a dietary supplement, take 2 capsules 1 to 2 times daily.

4) Life Extension Cognitex Basics

Life Extension Cognitex Basics (Brain Health Formula), 30 Softgels

Product Overview

  • Supports healthy brain cell function;
  • Enhances cognitive function as a nootropic supplement;
  • Dietary supplement.

What Is Life Extension Cognitex Basics

Life Extension Cognitex Basics formula dates back from 1982 when Life Extension developed it with the purpose to provide support for the brain of aging people. Today's Cognitex Basics is a less expensive yet very powerful product, featuring two important compounds that can't be supplied through adequate nutrition:

L-alpha glyceryl phosphorylcholine (Alpha-GPC) is naturally occurring in the membrane of most cells in the human body. Cognitex provides this compound as an essential building block for acetylcholine production in the brain.

Our brain needs acetylcholine for muscle control, sleep and cognition processes. Alpha-GPC helps to recycle phospholipids, so the more you have, the better your phospholipid synthesis.

The result is more efficient signal transduction by the central nervous system. Phosphatidylserine (PS) is another essential building block in the human brain. It can be found in most brain tissues.

​Nonetheless, aging can cause a decrease in the PS content of the tissues, therefore leading to cognitive decline. Phosphatidylserine plays a very important role in the healthy cellular division of nerves and in supporting the memory functions.

How to Use This Product

Take two (2) softgels daily with or without food.

5) Cognitex Elite Pregnenolone

Cognitex with Pregnenolone & Brain Shield 90 softgels-Pack-2

Product Overview

  • Foundation for longer life;
  • Enhances cognitive function as a nootropic supplement;
  • Dietary supplement.

What Is Life Extension Cognitex Elite Pregnenolone

Brain decline is something that affects all human bodies. Studies show that it is possible to maintain cognitive abilities and delay brain decline by providing the body with the right nutrients. 

Life Extension Cognitex Elite Pregnenolone has the following brain-boosting compounds gathered together in this unique formula that makes this product so special:

  • Gastrodin, also known as the "brain shield" - slows down and prevents oxidative processes and excitatory damage of brain cells. Its multiple mechanisms of action help protect the brain against age-related damage.
  • Alpha-glyceryl phosphorylcholine increases the production of acetylcholine, the neurotransmitter which helps brain cells to communicate, therefore being useful in memory and learning. Acetylcholine levels get on a descendant trend as we age past 30.
  • Vinpocetine boosts the oxygenation and the electrical conductivity of brain cells, helping also support the blood flow.
  • Hops and Rosemary have the ability to eliminate inflammatory cytokines.
  • Wild Blueberry Extract slows down oxidative processes and inflammation in brain cells, thus playing a role in stopping memory decline caused by these processes.
  • Phosphatidylserine (PS) has the proven ability to improve cognitive skills. This property has been demonstrated in multiple studies. 
  • Ashwagandha inhibits acetylcholinesterase, the enzyme which processes acetylcholine.
  • Grape seed extract is good for maintaining the oxygenation levels of the brain.
  • Uridine-5'-monophosphate (UMP)is a compound essential to humans when brains are the youngest. It is naturally found in the milk of nursing mothers and. Uridine also supports the cognitive function in aging adults.

How to Use This Product

Take three (3) softgels in the morning with or without food.


What Are Nootropics

Nootropics are cognitive enhancing supplements used to boost memory power and improve concentration. The nootropics are mostly used to help individuals focus, as study aids and attention spans increase. Very often Nootropics are referred to as “smart drugs” because they are related to increased intelligence, motivation, and mental energy.

The original definition of Nootropics comes from Belgian pharmacologists. Their names are S. Giurgea and V. Skondia and they invented the first Nootropic in 1963 - Piracetam. Both established the classification of Nootropics as cognitive boosting substances with very low toxicity, safe to be taken for a long-term period.

This fact proves that Piracetam and other Nootropics can improve brain functions without any adverse side effects associated with strong brain stimulants. We can conclude that nootropics are any type of neuro-enhancing drug or natural supplement with a very low prevalence of side effects. 

What Are Nootropics and How Do They Work

This post will provide an essential guide to the best nootropics for memory and give you a short overview of how to use these supplements to enhance your mental capabilities.

Best nootropics for memory

The Importance of Acetylcholine Levels for the Brain

First and foremost, you need to know about acetylcholine (ACh) levels. It is one of the most important neurotransmitters that is used by the body for facilitating connections between synapses and neurons.

You can enhance synaptic plasticity by increasing the level of acetylcholine in your body. Therefore, the best nootropics to enhance your memory are the ones that stimulate the production of acetylcholine and also cause the acetylcholine to be broken down more slowly.

The most powerful supplements available today for enhancing the production of acetylcholine in the body are racetams. For this purpose, pramiracetam, oxiracetam, and piracetam are considered the best.

For most people, Pramiracetam or Oxiracetam give the results they need, but you can significantly enhance the results by adding in a choline supplement.

If you want to get the maximum effect from the nootropics, you are taking you to need to have enough choline in the body which is used by the body for making ACh.

The two choline sources recommended by us as far as the best nootropics supplements available in the market for memory improvement is concerned Alpha GPC and CDP Choline (citicoline).

Use Choline Nootropics for Memory Enhancement

Alpha-GPC for Boosting Memory

As far as the recommended amount of this supplement is concerned, it's recommended to take a dosage of 1200 mg on a daily basis. You can also divide the dosage into multiple doses of 400 mg that can be taken three times each day.

Most manufacturers do not recommend dosage as high as 1200 mg as they usually recommend between 300 to 600 mg.

Keep in mind that there are absolutely no studies that prove that such a low dosage can have any impact on your cognitive abilities or memory.

How Does Alpha-GPC Work as a Memory Booster

Alpha-GPC is one of the most commonly used memory nootropics available in the market for enhancing cognition due to its ability to enhance the level of ACh in your body as acetylcholine is essential for making of short as well as long-term memory.

In addition to enhancing the levels of ACh in the body, it also helps in improving blood circulation to the brain. More blood in the brain means essential nutrients that provide fuel to the brain and keep it healthy and strong.

CDP-Choline (Citicoline) for Memory Enhancement

Studies show that it is safe to take anywhere between 500 mg - 2 g per day, however, higher dosages are more common among those who have experienced serious symptoms of cognitive declines, such as stroke survivors.

For most people's purposes, taking 250-500 mg twice daily is more than enough.

How Does CDP-Choline Work

CDP Choline (short for cytidine diphosphate-choline) is also known as Citicoline, this nootropic is pretty powerful on its own or in a stack. Citicoline enhances many cognitive functions related to learning, memory, and focus.

It works by synthesizing phosphatidylcholine — a major component of your brain's gray matter. It also nourishes nerves and improves blood circulation to the brain. CDP-Choline increases the level of acetylcholine, which is vital to memory formation.

Use the Most Powerful Nootropics for Memory - Racetams

Oxiracetam for Memory

As far as the recommended daily dosage is concerned, it is recommended to take 800 to 2400 mg. You can also take three separate doses of 800 mg to get to the daily dosage of 2400 mg, but experts recommend starting at a lower dosage and then work your way up.

It will help you in seeing whether it is having the desired effect on your body and then you can adjust the dosage as needed. In capsule form, the most common dosage available in the market is 750 mg, but you can also buy the powder on your own and create your dosage.

Also, it's important to mention here that you can easily take it on an empty stomach as it is a water-soluble nootropic.

How Does Oxiracetam Work for Enhancing Memory

It is an ampakine similar to Noopept. The primary function of this supplement is to enhance the production of ACh in the body as well as the NMDA glutamate neurotransmitters.

By enhancing the production of these neurotransmitters, it helps in improving short-term as well as long-term memory formation, and it also helps in enhancing memory retention. This is the reason this particular supplement is so popular among students.

Pramiracetam and Cognition

Since it is a fat-soluble nootropic, it means you can get better results at even smaller dosages. As far as the daily dosage is concerned, the recommended average daily dosage ranges from 400 to 1200 mg.

However, if you want to get the best results, you may take a dosage of 400 mg thrice on a daily basis to get the best results. Some people like to take it with food whereas others do not, and therefore, it is recommended to do your little trial and error to make it work for you.

Since it is a fat-soluble nootropic, its results are likely to last much longer as compared to a water-soluble nootropic. You need to be aware of this before you start taking it.

How Does Pramiracetam Work for Cognition

This supplement offers a variety of cognitive benefits such as better memory and cognition which makes it an excellent supplement for studies and you can also use it to improve your memory in the day to day life.

It is absorbed into the bloodstream through lipids from where it gets into the brain. On passing the blood-brain barrier, it helps in modulating the receptor sites for ACh. In simple terms, it helps in enhancing the circulation of acetylcholine in the brain by binding to the receptor sites.

It also helps in improving the neuron impulse flow which helps in the formation and storage of new memories. You can also is the level of ACh in your brain by consuming another natural nootropic known as Huperzine A that helps in preventing the breakdown of ACh.

In simple terms, it works as an acetylcholinesterase inhibitor. It has shown significant results in improving the mental health, memory functions and learning functions in elderly patients.

In fact, research is going on to make it a part of herbal treatment for replacing various medications for the treatment of Alzheimer's disease. One of the ways to enhance your memory function is to take this supplement in the right dosage levels.

You may find it difficult to buy this nootropic on its own, but some solid nootropics stacks such as Alpha Brain have it in a decent amount.

Tip #1: Increase Glutamate Uptake for Memory Boost

Of all the neurotransmitters in the brain, glutamate is found in the greatest abundance. It has a huge role in the communication that goes on between neurons. This is also a chemical that is in charge of creating synaptic plasticity.

It determines how quickly you will make new connections and how easily you will retrieve memories. Nootropics that increase glutamate levels are Ampakines. These are known for increasing the receptors in the brain known as AMPA and NDMA.

There is a lot of research being done on synthetic ampakines today and the best include racetams such as Aniracetam and Piracetam. L-Theanine is another glutamate precursor. It is an amino acid found in green tea. It works well when it is used with caffeine.

To get nootropic benefits from theanine, you need to take it in high dosages of at least 200 mg. This is similar to what is found in Nootrogenix (see below for this product).

Tip #2: Increase Blood and Oxygen to the Brain

Your brain needs oxygen for everything that it does. The more blood that gets pumped to the brain the more it increases the brain's oxygenation level. This means there is more energy available for mental tasks. If you can increase your oxygen flow just a little, you will get much more energy.

With that extra energy, you will be able to concentrate better, have greater awareness and more motivation. You will also get more improved memory and better learning abilities. The racetams that increase the brain's blood flow include Oxiracetam and Piracetam.

The best nootropic for memory and increased oxygen flow to the brain includes Vinpocetine. This is very effective and improving the blood flow to the brain. Vinpocetine is an herbal nootropic, so it is all-natural.

Vinpocetine is can also be neuroprotective and can help your brain cells live longer and stay in better shape. This means you get many more benefits from this nootropic where memory is concerned.

So Which Nootropics Gives the Best Memory Results

As I already expose above, there are many nootropics available that work great for improving memory. But what is the best way to make use of these supplements? If you only choose to use one, you want to choose Oxiracetam or Aniracetam.

Both of these are excellent memory enhancers. You should also remember to supplement the racetam you choose with other nootropics like choline. Choline is found in Alpha GPC and is also found in Huperzine A, Vinpocetine, and L-Theanine.

It can be inconvenient to buy these herbal compounds separately. This is one reason you should look for brain stack products like Nootrogenix. It gives you all these ingredients together with some additional herbal supplements for memory enhancement.

Last Updated on June 27, 2024 by Kaira


Written by Nick J-Pepe

Nick is the founder of planculde.com. He's been nuts about sports since kindergarten. He practices the 80/20 rule of eating, and being the cool guy is just his DNA.


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